Sep 23, 2019 not known whether papaverine distributes into human milk. Papaverine hydrochloride injection fda prescribing. Papaverine hydrochloride monograph for professionals. Papaverine hydrochloride solutions ampouled under conditions were stable during two years of storage at room temperature. Papaverine hydrochloride solution for injection drug summary. Papaverine hydrochloride solution for injection 30mg drug. However, children have received papaverine hydrochloride dosages of 6 mgkg daily, divided into 4 im or iv doses.
Dailymed papaverine hydrochloride injection, solution. Dec 06, 2019 papaverine hydrochloride occurs as white crystals or white crystalline powder. This drug has not been found by fda to be safe and effective, and this labeling has not been approved by fda. Papaverine hydrochloride api manufacturers suppliers drug. Papaverine hydrochloride occurs as white crystals or white crystalline powder. Papaverine hydrochloride 61256 tokyo chemical industry uk ltd. Papaverine side effects, dosage, interactions drugs.
Papaverine hydrochloride injection, usp safety data sheet according to federal register vol. Firstaid measures general advice show this safety data sheet to the doctor in attendance. Nov 09, 2018 papaverine is a vasodilator that relaxes smooth muscles in your blood vessels to help them dilate widen. Suitable respiratory protective device recommended. A simulation of intraarterial infusion for cerebral vasospasm john m. A study of the stability of papaverine hydrochloride solutions. Identification of the substancemixture and of the companyundertaking. Papaverine hydrochloride papaverine hydrochloride injection solution. All spectrum chemical usp grade products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered. Papaverine hydrochloride, usp 61256 pa126 spectrum.
Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Stability of papaverine hydrochloride and phentolamine mesylate in injectable mixtures. Papaverine hydrochloride solution for injection drug. Other companies are charging thousands of dollars to set up accounts and give you access to their msds. Papaverine hydrochloride, for parenteral administration, is a smoothmuscle relaxant that is available in vials containing 30 mgml. Papaverine hydrochloride api manufacturers suppliers. Papaverine hydrochloride injection, usp rx only papaverine hydrochloride injection, usp rx only. Papaverine is an opium alkaloid antispasmodic drug, used primarily in the treatment of visceral spasm, vasospasm especially those involving the heart and the brainin vivo. Papaverine hydrochloride solutions ampouled under conditions were stable during two years. Papaverine hydrochloride is a selective phosphodiesterase inhibitor for the pde10a subtype found mainly in the striatum of the braintarget. Assay dissolve about 700 mg of papaverine hydrochloride, accurately weighed, in 80 ml of glacial acetic acid. As of 20, this field contains the consumer friendly descriptions for the ama cpt codes. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas. Papaverine hydrochloride c20h22clno4 cid 6084 structure, chemical names, physical and chemical properties, classification, patents, literature, biological.
Safety data sheet according to 29cfr19101200 and ghs rev. Only select registry of toxic effects of chemical substances rtecs data is presented here. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Papaverine hcl is a vasodilator that causes blood vessels to expand resulting in increased blood flow. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. It is shown that the ph range of solutions ampouled in an inert gas medium is 2. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking papaverine. The substance identity section is calculated from substance identification information from all echa databases.
Papaverine hydrochloride usp about fagron fagrons strategy is focused on the optimization and innovation of pharmaceutical compounding. Papaverine hydrochloride, c 20 h 21 no 4 hcl, is a white, crystalline powder, odorless, with a slight bitter taste and is soluble in water. Material may be irritating to the mucous membranes and upper respiratory tract. Section 1 identification of the substancemixture and of the. Stability of papaverine hydrochloride and phentolamine. Papaverine hydrochloride, usp is an opium alkaloid antispasmodic drug. Find patient medical information for papaverine injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
As a directacting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions. Our msds database is an easy to use, do it yourself tool, and best of all. Papaverine hydrochloride 61256 buy and find out price and availability, msds, properties of tcis high quality specialty chemicals. Parchem is open and ready to supply materials 18002823982 read more. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Drotaverine is a selective inhibitor ofphosphodiesterase 4, and has no anticholinergic effects. J2440 hcpcs code papaverin hcl injection hcpcs registry. Papaverine hydrochloride substance information echa. Repeated exposure to low concentrations of hcl vapor or mist may cause. One gram dissolves in about 30 ml of water and in 120 ml of alcohol. Papaverine injection papaverine hydrochloride injection. This drug increases blood flow to the penis when it is injected into the penis resulting in an erection. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. This lowers blood pressure and allows blood to flow more easily through your veins and.
It is a directacting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. It is soluble in chloroform and practically insoluble in ether. Papaverine hcl usp sds preparation date 06222017 page 4 of 8 safety data sheet section 8 exposure controlspersonal protection continued breathing equipment. This product is to be used by or under the direction of a physician. Suppliers list, emailrfq form, molecular structure, weight, formula, iupac, synonyms for papaverine hcl cas no. Safety and efficacy of papaverine in pediatric patients not established. Application papaverine hydrochloride has been used. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Empirical formula hill notation c 20 h 21 no 4 hcl. Sigmaaldrich offers a number of papaverine hydrochloride products. Papaverine hydrochloride belongs to the group of benzylisoquinoline alkaloid.
In vitro anticancer effects of a rage inhibitor discovered using a. This drug is used for the production of erections in some men with erectile dysfunction. Papaverine hydrochloride cas 61256 scbt santa cruz. Papaverine was discovered in 1848 by georg merck 18251873. General papaverine hydrochloride injection, usp, should not be added to lactated ringers injection, because precipitationwouldresult. An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. Chemicalbook provide chemical industry users with papaverine hydrochloride boiling point melting point,papaverine hydrochloride density msds formula. Eye contact in the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. The phsolubility profile of papaverine hydrochloride i was determined using the phasesolubility technique and equilibrium solubilities in buffers. Papaverine is an opiate alkaloid isolated from the plant papaver somniferum and produced synthetically.
Papaverine hydrochloride ask price drotaverine inn, also known as drotaverin is an antispasmodic drug, structurally related to papaverine. Papaverine hydrochloride sustained release capsules, 150 mg. Papaverine hydrochloride drug information, uses, side. Synonyms papaverine hcl unii 23473ec6bq cas number 61256 weight average.
Papaverine is a vasodilator that relaxes smooth muscles in your blood vessels to help them dilate widen. See actual entry in rtecs for complete information. Papaverine hydrochloride injection, usp, is a clear, colorless to paleyellow solution. Along with its needed effects, papaverine may cause some unwanted effects. Papaverine hydrochloride solution for injection 30mg drug medication dosage information. Perform a blank determination, and make any necessary correction. Papaverine hcl, papaverine hcl supplier, papaverine hcl distributor, cas 61256, papaverine hcl manufacturer, papaverine hcl wholesale skip to main content covid19 status. In vitro evaluation of papaverine hydrochloride incompatibilities. The stability of papaverine hydrochloride and phentolamine mesylate combined in a single vial was studied.